Friday, October 10, 2008

Research on Depression

If you like to read research articles here are the articles I have referenced so far:


  • PMID: 11552767; A systematic review and meta-analysis of Hypericum perforatum ion depression: a comprehensive clinical review. Int Clin Psychopharmacol. 2001 Sep;16)5):239-52.
  • PMID: 11939866; Effect of Hypericum perforatum (St. John’s wort) in major depressive disorder: a randomized controlled trial. JAMA. 2002 Apr 10;287(14):1807-14.
  • PMID: 11308434; Effectiveness of St. John’s wort in major depression: a randomized controlled trial. JAMA 2001 Apr 18;285(15):1978-86.
  • PMID: 12053635; St John’s wort or sertraline? Randomized controlled trial in primary care. Can Fam Physician. 2002 May;48 :905-12.
  • PMID: 16160619; A Double-blind randomized trial of St. John’s wort, fluoxetine, and placebo in major depressive disorder. J Clin Psychopharmacol. 2005 Oct; 25(5):441-7.
  • PMID: 9539254; Vitamin D3 enhances mood in healthy subjects during winter. Psychopharmacology (Berl). 1998 Feb;135(4):319-23
  • PMID: 386715; Symptom reduction in depression after treatment
  • PMID: 11679026; Passionflower in the treatment of generalized anxiety: a pilot double blind randomized controlled trial with oxazepam. J Clin Pharm Ther. 2001 Oct; 26(5): 363-7.
  • PMID: 12888186; Omega 3 fatty acids in major depressive disorder. A preliminary double-blind, placebo-controlled trial. Eur neuropsycholparmacol. 2003 Aug;13(4):267-71.
  • PMID: 12365878; A dose-ranging study of the effects of ethyl-eicosapentaenoate in patients with ongoing depression despite apparently adequate treatment with standard drugs. Arch Gen Psychiatry. 2002 Oct;59(10);913-9.
  • PMID: 10967371; Enhancement of the antidepressant action of fluoxetine by folic acid; a randomized, placebo controlled trial. J Affect Disord. 2000 Nov; 60(2):121-30.
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DISCLAIMER:

This website is intended for educational purposes only. Read our full disclaimer. Always work with your physician for proper care and supervision. I strictly advise AGAINST combining herbs or natural therapies (aside from vitamins, minerals, or fish oil) with any form of anti-depressants. Although it is occasionally done, most naturopathic physicians, MD’s, and psychiatrists agree that until we have research demonstrating efficacy and safety herbs and natural anti-depressants with similar mechanisms to prescription drugs should not be simultaneously used. Also, although these medicines are “natural” they are still medicines. Please do not choose to discontinue your natural medicines without the advice of your physician, someone should be overseeing your care. Depression is complicated to sort out. Please do not try to do it alone. Someone needs to be documenting your mood fluctuations as well as when you start and stop specific therapies. Never make any changes to your health without first consulting with your physician. Have your physician check for drug interactions, and always be cautious when combining natural medicines and drugs for depression as the life threatening condition "Serotonin Syndrome" may occur. Work directly with a physician in regards to your bi-polar or depression.